Methadone Side Effects | Dosage, Interaction & Vital Information

Side Effects of Methadone:

Medicines and drugs may lead to some side effects, but lots of people have no side effects, or slight side effects. Confirm with the doctor if a few of these COMMON side effects endure or turn out to be bothersome while using Methadone:

  • Dizziness;
  • Constipation;
  • Dry mouth;
  • Drowsiness;
  • Increased sweating;
  • Headache;
  • Lightheadedness;
  • Itching;
  • Vomiting;
  • Nausea;
  • Weakness.


It is recommended that you request medical attention without ado if any SEVERE Methadone side effect occurs when with Methadone:


Severe allergic reaction like:

  • Rashes;
  • Hives;
  • Itch;
  • Trouble breathing;
  • Tension in chest;
  • Puffiness of the face, lips, mouth, or tongue);
  • Confusion;
  • Decrease in sexual ability or desire;
  • Excessive drowsiness;
  • Sensation like you might faint;
  • Fast, sluggish, or unbalanced heartbeat;
  • Loss in appetite;
  • Hallucinations;
  • Psychological or mood change (for e.g., agitation, perplexity, exaggerated feeling of well-being);
  • Severe or unrelenting dizziness or wooziness;
  • Menstrual changes;
  • Shortness in breath;
  • Seizures;
  • Slow or thin breathing;
  • Trouble sleeping;
  • Puffiness of the feet, arms, or legs;
  • Difficulty urinating;
  • Strange blood loss or bruising.


Stop using Methadone and get in touch with your health care provider immediately if you face a serious Methadone side effect for instance:

  • Trivial breathing;
  • Confusion or hallucinations ; or
  • Chest soreness, fainting, dizziness, rapid or hammering heartbeat; or
  • Problem breathing, sensation of light-headedness, or fainting.


Less grave side effects of methadone may consist of:

  • Feeling nervous, anxious, or restless;
  • insomnia or Trouble Sleeping;
  • Feeling frail or drowsy;
  • Dryness in mouth, nausea, diarrhea, vomiting, constipation, loss in appetite; or
  • Decrease in sex drive, trouble reaching an orgasm or impotence.


About Methadone:

Methadone’s a narcotic soreness reliever, somewhat like morphine. In addition, Methadone lessens the withdrawal symptom, which crop up in patients who are addicted to heroin or any additional narcotic drug, without resulting in the “high” which is associated to the drug dependence.

Methadone is made use of as a pain alleviator and as fraction of drug dependence detoxification as well as maintenance programs.

When the drug is used for detox, it is actually substituting methadone for a traditional substance of abuse like heroin.

Vital Information Regarding Methadone:

Using methadone inappropriately will raise your risks of grave side effects of methadone or even fatality. Even in the case where you have made use of other narcotic medication, you might still have grave side effects resulting from methadone. Pursue all dose instructions cautiously.

Like all other narcotic medication, methadone is capable of slowing down your inhalation, even long subsequent to the pain-alleviation property of the drug wears off. Casualty may come about if a person’s breathing turn out to be too frail. Never take extra methadone than what your health care provider has prescribed for you. Get in touch with your health care provider if you feel the medication is not working as it should.

Don’t discontinue using methadone all of a sudden, or you might have disagreeable withdrawal symptoms. Get in touch with your health care provider if you fail to notice doses or overlook to consume this drug for more than 3 days consecutively. Don’t consume alcohol while you’re taking methadone. Hazardous side effects or casualty can crop up once alcohol is pooled with methadone. Be sure to check your medicine and food labels in order to be certain these products don’t contain alcohol. This drug can source methadone side effects that might impair your thoughts or responses. Be cautious if you are to drive or do something that needs you to be alert and ready to act.

Prior To Taking Methadone:

Methadone could be addictive and ought to be made use of only by people that it has been prescribed for by their health care provider’s. Methadone must never be offered to another individual, in particular someone who’s had an account of addiction or drug abuse. Keep the medicine in a safe and sound place where no other person can reach or find it. Don’t use this drug if you’ve ever had an allergy to any narcotic drug (for example morphine, codeine, Darvocet, Oxycontin, Vicodin, Percocet, Lortab, etc.). You must also never use methadone in case you’re susceptible to asthma attacks or are having one or in case you have bowel obstruction known as paralytic ileus.

Prior to using methadone, inform your health care provider in case you have:

  • COPD, asthma, sleep apnea, or any additional breathing disorders;
  • Any personal or ancestral record of “Long QT disorder”;
  • Kidney or liver ailment;
  • Curvature of spine;
  • Underactive thyroid;
  • A record of brain tumor or head injury;
  • Epilepsy or any other seizure disarray;
  • Stumpy blood pressure;
  • Gallbladder sickness;
  • Addison’s syndrome or additional adrenal gland disorder;
  • Urination problems, Enlarged prostate;
  • Psychological illness; or
  • A record of alcohol or drug obsession.


This drug might be harmful for an unborn child. It could moreover reason withdrawal symptoms or addiction in an infant in case the mother uses methadone for the duration of pregnancy. Inform your health care provider if you’re pregnant or planning for a pregnancy for the duration of treatment. Methadone is capable of passing into a nursing mother’s breast milk and might cause harm to a nursing newborn. Don’t use this drug without letting your health care provider know if you’re breast-feeding a newborn.

Older adults as well as individuals with debilitating state might be further susceptible to the effect of this drug.

How to use methadone:

Take methadone accurately as it has been prescribed to you. Don’t use the drug in bigger amounts or even for longer duration than suggested by your health care provider. Pursue the instructions on your treatment label.

When this drug is made use of as fraction of a treatment plan for drug dependence or detoxification, you’ll receive the prescription through a special pharmacy or a doctor’s office.

Your health care provider might suggest that methadone be administered to you via a caregiver or some family member. This is done to make sure you’re taking the medication as it has been prescribed as component of the treatment.

Further forms of monitoring and/or counseling might be suggested during the treatment using methadone.

Methadone is accessible in dispersible tablets, tablets, injection and as an oral or liquid solution. The oral liquid and pill form of methadone should never be made use of to create a methadone shot (injection).

Determine the liquid variety of methadone using a unique dose-measuring cup or spoon, not a normal table spoon. In case you don’t have a quantity-measuring tool, ask any pharmacist for the same.

The dispersible methadone tablets (or Diskets) are meant to be liquefied in water. Don’t crush, chew, or gulp the tablet complete. Put the tablet in 4-ounces of orange juice, water, or any other non-alcoholic citrus-flavored drink and let the pill to dissolve within the liquid. The pill will not disband completely. Swallow this combination right away. In order to be sure you obtain the entire prescribed amount, add slightly extra liquid into the glass, gently swirl and gulp right away.

Stock up methadone away from heat and moisture and keep at room temperatures.

Keep a track of the quantity of this medication that has been made use of. Methadone is a medicine of abuse and one should be conscious if anybody in the family circle is taking this medication inappropriately or without a recommendation.

In Case You Forget A Dose:

Use the dose that you have missed the instant you remember. Leave out the dose that you have missed in case it’s more or less time for the next planned prescribed amount. Don’t use extra drug to make up for the dose that you have missed. In case you overlook your dose for more than 3 days one after the other, get in touch with your health care provider for directions. You might have to restart your methadone treatment at a smaller dose.

In Case Of an Overdose:

Call a help line immediately or request immediate emergency health attention if you feel you have taken too much of this drug. A methadone overdose could be lethal, particularly if you use it with any narcotic medications or alcohol.

Overdose symptoms for methadone may consist of fainting, intense drowsiness, confusion, pinpoint pupils, clammy and cold skin, shallow breathing, weak pulse, or breathing which stops.

Things to Avoid While Using Methadone:

Don’t consume alcohol while you’re taking methadone. Hazardous side effects or casualty can crop up once alcohol is pooled with methadone. Be sure to check your medicine and food labels in order to be certain these products don’t contain alcohol. This drug can source methadone side effects that might impair your thoughts or responses. Be cautious if you are to drive or do something that needs you to be alert and ready to act.


Stock up at room temperatures, away from moisture and light. Don’t hoard inside the bathroom. Store all medicine away from pets and children. Don’t flush any medication in the toilet or into the drain, except for when you have been instructed to. Properly dispose of this medicine when it expires or is no longer required. Check with your doctor or local waste clearance company for further details on the subject of how to securely discard the medications.

Drugs That Will Have an Effect On Methadone:

Don’t use methadone with other narcotic pain medications, sedatives, tranquilizers, muscle relaxers, or other medicines that can make you sleepy or slow your breathing. Dangerous side effects may result. Don’t use methadone with any of the following drugs without first talking to your health care provider:


  • Any diuretic (also known as water pill);
  • Any antibiotics for instance ciprofloxacin (Cipro), azithromycin (Zithromax), erythromycin (Ery-Tab, E-Mycin),  clarithromycin (Biaxin), ketoconazole (Nizoral), itraconazole (Sporanox), voriconazole (Vfend) or metronidazole (Flagyl);
  • Any blood pressure or heart medication for instance verapamil (Covera, Calan, Verela,  Isoptin) or diltiazem (Dilacor, Cardizem, Tiazac) ;
  • HIV medicines for instance amprenavir (Agenerase), abacavir (Ziagen), efavirenz (Sustiva), didanosine (Videx), nelfinavir (Viracept),  ritonavir /lopinavir (Kaletra), ritonavir (Norvir), nevirapine (Viramune), zidovudine (Retrovir) or stavudine (Zerit);
  • Any MAO inhibitor for instance tranylcypromine (Parnate),  isocarboxazid (Marplan), selegiline (Emsam, Eldepryl) or phenelzine (Nardil);
  • Any other narcotic medication for instance nalbuphine (Nubain), pentazocine (Talwin), butorphanol (Stadol) or buprenorphine (Subutex);
  • Rifampin (Rimactane, Rifadin, Rifater);
  • Any seizure medication for instance phenytoin (Dilantin) or phenobarbital (Solfoton, Luminal) .