Losartan Side Effects |Dosage, Interaction & More

Losartan Side Effects

Medicines and drugs may lead to some side effects, but lots of people have no side effects, or slight side effects. Confirm with the doctor if a few of these COMMON side effects endure or turn out to be bothersome while using Losartan:

  • Giddiness;
  • Diarrhea;
  • Tiredness.

It is recommended that you request medical attention without ado if any SEVERE Losartan side effect occurs when with Losartan:

Severe allergic reaction like:

  • Rashes;
  • Hives;
  • Itch;
  • Trouble breathing;
  • Tension in chest;
  • Puffiness of the face, lips, mouth, or tongue;
  • Huskiness;
  • Alter in the quantity of urine formed;
  • Chest soreness;
  • Trouble swallowing;
  • Dark urine;
  • Hasty, slow, or unbalanced heartbeats;
  • Muscle soreness or cramps;
  • Harsh or unrelenting stomach ache (without or with unsettled stomach or vomiting);
  • Indications of stumpy blood pressure (for e.g., fainting, harsh dizziness, nausea);
  • Strange bleeding or bruising;
  • Yellowing in skin or eyes
  • Vision change.

Drug Class and Mechanism:

Losartan’s an oral drug that comes from a group of drugs known as ARB’s or angiotensin receptor blockers. Some examples of ARBs consist of candesartan (Atacand), valsartan (Diovan), as well as irbesartan (Avapro). Angiotensin, created within the blood through the actions of ACEs or the angiotensin converting enzymes, is a dominant chemical which joins with angiotensin receptors that are found in numerous tissues but mainly on the smooth muscle cell of the blood vessels. An Angiotensin connection with the receptors is what causes the blood vessel to contract (vasoconstrict) and that leads to a swell in hypertension, also known commonly as blood pressure. The drug Losartan (more exclusively, the compound created when a person’s liver changes inactive Losartan to a dynamic chemical) obstructs the angiotensin receptors. By obstructing the actions of angiotensins, Losartan dilates the blood vessels, thereby reducing blood pressure. This drug was permitted by FDA sometime during April 1995.

 

Preparations:

Pills: 25mg, 50mg as well as 100 mg

 

Prescribed For:

This drug is made use of for treatment of hypertension, diabetic nephropathy (or kidney ailment) and left ventricular hypertrophy (i.e. a boost in muscle). Losartan may be made use of unaccompanied or even in amalgamation with additional medicines.

 

Dosing:

The starting prescribed amount for Losartan in an adult is usually50 mg, on a daily basis. The maximum dosage can be 100 mg on a daily basis. The overall daily dosage may be separated and administered two times each day. Losartan might be taken with food or even without it.

The starting prescribed amount for Losartan in a pediatric patient who is 6 years in age or even older, is usually from 0.7 mg/kg to 50 mg, one time, on a daily basis.

 

 

 

About Losartan:

Losartan comes from a cluster of drugs known as angiotensin II receptor antagonists. The drug keeps the blood vessel from tapering, which then lowers the blood pressure in addition to improving blood stream.

Losartan is made use of to take care of lofty blood pressure (or hypertension). Furthermore, it’s used to lessen the risks of a stroke in some people suffering from heart diseases.

Losartan is made use of to slower enduring kidney damages in individuals who have type 2 diabetes along with elevated blood pressure.

 

Vital Information Regarding Losartan:

Don’t take Losartan if you’re pregnant. Losartan could hurt the unborn child. Discontinue using this drug and inform your health care provider right away in case you turn out to be pregnant at some stage in Losartan treatment. You must not take this drug if you’re sensitive to Losartan. Consuming alcohol can advance lowering blood pressure levels and might increase Losartan some side effects. Don’t use potassium add-ons or salt replacements while you’re using Losartan, except for when your health care provider has asked you to do the same.

A patient’s blood pressure must be checked time and again. Visit your health care provider on a regular basis.

Continue using this drug even if you’re feeling in good health. Lofty blood pressure often shows no signs or symptoms.

In exceptional cases, Losartan could cause a situation that result in the collapse of the skeletal muscle tissues, resulting in kidney malfunctions. Get in touch with your health care provider right away in case you face muscle soreness, weakness or tenderness, particularly in case you also face fever, dark color urine and unsettled stomach or vomiting.

 

Drug Interactions:

An Inhibitor of cytochrome P450 enzyme for instance fluconazole (Diflucan) condensed the creation of the dynamic drug metabolites in laboratory researches. Therefore, vigilance should be taken when adjoining Losartan in patients using Nizoral, since condensed action of Losartan might occur.

 

Losartan might increase the level of blood potassium that could lead to grave heart troubles (arrhythmias). As a result, concomitant application of additional substances that swell blood- for instance potassium-sparing diuretic (for instance, amiloride, triamterene, and spironolactone (Aldactone), potassium add-ons, or salt replacements containing potassium–might lead to hazardous increase in the serum potassium.

 

Antihypertensive effects of Losartan might be condensed by anti-inflammatory nonsteroidal drugs (for instance, ibuprofen, indomethacin, naproxen and aspirin).

Drug interactions might modify how your medication works or raise your risks for grave side effects. Keep a file of every product you take (including non-prescription/prescription medicines as well as herbal products) so you can share this with your health care provider and pharmacist. Don’t begin, discontinue, or alter the dose of any drug without your health care provider’s consent. Products that might intermingle with this treatment takes account of: lithium.

 

Nursing Mothers:

 It’s not acknowledged whether or not Losartan can pass in breast milk. Owing to the likelihood of impairment to a nursing newborn, if likely, Losartan must be stopped by a nursing mother.

 

Pregnancy:

When taken during the 2nd or 3rd trimester in pregnancy, medicines that operate by a similar method as Losartan (or ARBs) could cause damage and even fatality to a fetus. Losartan must not be taken for the period of pregnancy. As soon as pregnancy is detected, the drug Losartan must be discontinued immediately.

 

 

Prior To Using Losartan:

You must not take this drug if you’re sensitive to Losartan.

In case you face any of the below mentioned conditions, you might need a dosage alteration or particular tests:

 

  • Liver ailment;
  • Kidney ailment;
  • Congestive heart malfunction;
  • In case you’re dehydrated;
  • Any electrolyte disparity (for instance squat levels of potassium present in blood);

 

Don’t take Losartan if you’re pregnant. Losartan could cause harm to an unborn child. Discontinue using this prescription and inform your health care provider right away in case you turn out to be pregnant. Losartan could cause damage or casualty to an unborn child if you use the medicine for the period of your 2nd or 3rd trimester pregnancy. It’s not acknowledged whether or not Losartan is capable of passing into a nursing mother’s breast milk or in case it is capable of causing harm to a nursing newborn. Don’t use this prescription without notifying your health care provider in case you’re breast-feeding a newborn.

How to Use Losartan:

 

Take precisely as approved by your health care provider. Don’t use in bigger or lesser amount or even for longer duration than suggested. Follow the instructions on your treatment label.

Your health care provider might occasionally alter your dosage to make certain you obtain the maximum results.

You might use Losartan with food or without it.

Get in touch with your health care provider in case you have constant diarrhea or vomiting or in case you’re sweating greater than normal. You can simply become dehydrated when taking this drug, which could lead to harsh and stumpy blood pressure level or a grave electrolyte disproportion.

A patient’s blood pressure must be checked time and again. Visit your health care provider on a regular basis.

It might take 3- 6 weeks before a patient’s blood pressure comes under control. In order to get best results, continue using the prescription as instructed. Speak to your health care provider in case your warning signs don’t get better even after three weeks of Losartan treatment.

Continue using this drug even in case you feel in good health. Elevated blood pressure usually has no indications.

 

In Case You Miss A Dosage:

Take the dose that you have missed the moment you remember. Leave out the dose that you have missed if it’s approximately time for the next planned dose. Don’t use extra medication to make up for the dose that you have earlier missed.

 

In Case Of an Overdose:

Request immediate emergency health attention or get in touch with a Help line. Symptoms of an Overdose might consist of hasty or sluggish heartbeat, lightheadedness, or sensation like you may pass out.

 

Things to Avoid While Using Losartan:

Consuming alcohol could further lower down a patient’s blood pressure level and might swell certain Losartan side effects. Don’t use potassium add-ons or salt replacements while you’re using Losartan, unless the health care provider has asked you to do so. Avoid sitting up too quickly from a lying or sitting position, since you might feel lightheaded. Get up gradually and balance yourself to avoid a fall.

 

 

Drugs That Will Have an Effect On Losartan:

Notify your health care provider regarding all other drugs you use, in particular:

  • Any diuretic (also known as water pills);
  • Celecoxib (celebrex); or
  • Lithium (lithobid, eskalith, lithonate);
  • Other nsaids for instance diclofenac (voltaren, cataflam), ibuprofen (advil, motrin), indomethacin (indocin), etodolac (lodine), naproxen (naprosyn, aleve), nabumetone (relafen), piroxicam (feldene), meloxicam (mobic), or aspirin.

 

Storage:

Store pills at room temperatures away from moisture and light. Don’t hoard inside the bathroom. Store all medication away from pets and children. Keep the suspension inside the refrigerator, between 36 to 46o F. Don’t freeze. Dispose of any suspension that is unused if it’s been more than 4 weeks. Don’t flush medication in the bathroom or pour it into the drain unless you are told to do so. Appropriately discard this drug once it has reached its expiry date and is no longer required. Discuss with your neighboring waste disposal party or pharmacist for additional details on the subject of how to securely dispose of this medication.

email