Lisinopril (Zestril, Prinivil) Side Effects | Interactions & Vital Information

About Lisinopril:

Lisinopril belongs to an assembly of drugs known as ACE inhibitors (angiotensin converting enzyme).

The drug is made use of to cure elevated blood pressure or hypertension, to recover after a stroke or a heart attack and for congestive heart malfunctions.

Vital Information Regarding Lisinopril:

Don’t use this drug without informing your health care provider in case you’re pregnant or are planning for a pregnancy. The drug could lead to birth imperfections in the newborn in case you use the medicine at some point in your pregnancy. Draw on any efficient type of birth control. Discontinue using this drug and inform your health care provider right away in case you turn out to be pregnant at some stage in treatment.

Keep away from consuming alcohol. It could further lower down your blood pressure in addition to increasing a number of lisinopril side effects. Don’t take any salt replacements or potassium add-ons while using lisinopril, unless you have been permitted to do so by your health care provider.

Nausea, diarrhea, or profound sweating can lead you to befall dehydration. This could lead to extremely stumpy blood pressure, kidney failure, or electrolyte disorders while you’re using lisinopril. Consume ample amounts of water every day when you’re using this drug.

How to Use Lisinopril:

Use this drug accurately as it has been approved for you by your health care provider. Don’t use the medicine in bigger amounts, or use it for a longer duration than what has been recommended to you by your health care provider. Follow the instructions on your treatment label.

Your health care provider might seldom alter your prescribed amount to make certain whether or not you are getting the best outcome from this drug.

Take every prescribed amount along with a full tumbler of water.

The drug can be consumed with food or even without food.

In order to be certain if this drug is helping a patient’s condition, his/her blood pressure ought to be regularly tested on a usual basis. The patient’s liver or kidney function might also require standard testing. Don’t neglect any planned visits to your health care provider.

In case you need to undergo any sort of surgical procedure, inform the surgeon in advance that you’re using lisinopril. You might need to discontinue taking the medication for a short while.

In case you’re being cured for elevated blood pressure, continue using this drug even in case you feel all right. Elevated blood pressure, time and again, shows no symptoms.

It is recommended that you stock up lisinopril away from heat and moisture plus store it at room temperatures.

Prior To Consuming Lisinopril:                                                                                              

Don’t take this medicine if you’re sensitive to lisinopril or even to any additional ACE inhibitor, for instance captopril (Capoten), trandolapril (Mavik), benazepril (Lotensin), enalapril (Vasotec), fosinopril (Monopril), perindopril (Aceon), moexipril (Univasc), ramipril (Altace), quinapril (Accupril).


In case you have some conditions, you might call for a dosage adjustment or particular tests to securely use lisinopril. Prior to you using this medicine, inform your health care provider in case you have:

  • Liver ailment;
  • Kidney ailment (or in case you’re on dialysis);
  • Diabetes;
  • Heart ailment or congestive heart malfunction;
  • Any connective tissue ailment for instance rheumatoid arthritis, sjogren’s syndrome, marfan syndrome, scleroderma, lupus.


Don’t make use of this drug without notifying your health care provider in case you’re pregnant or are planning for a pregnancy. The drug could lead to birth flaws in the newborn in case you use the drug for the period of pregnancy. It’s not acknowledged whether or not lisinopril is capable of passing into a nursing mother’s breast milk or in case it is capable of causing harm to a nursing newborn. Don’t take this medicine without notifying your health care provider in case you’re breast-feeding your baby.

Things to Avoid Taking Along With Lisinopril:

Avoid any consumption of alcohol as it could further lower down a patient’s blood pressure and might also increase a number of lisinopril side effects of. Don’t consume any salt replacements or potassium add-ons while you are using lisinopril, unless you have consulted with and been permitted to do so by your health care provider.

In Case You Forget A Dose:

Consume ASAP as you remember.

In Case Of a Lisinopril Overdose:

Seek medical help ASAP. You might feel light headache, fainting etc..


Lisinopril Side Effects:

Medicines and drugs may lead to some side effects, but lots of people have no side effects, or slight side effects. Confirm with the doctor if a few of these COMMON side effects endure or turn out to be bothersome while using Lisinopril:

  • Diarrhea;
  • Cough;
  • Lightheadedness;
  • Headaches;
  • Tiredness.

Request immediate medical attention in case any of the below mentioned SEVERE lisinopril side effects crop up when taking Lisinopril:

Severe allergic reaction such as:


  • Rashes;
  • Hives;
  • Itch;
  • Trouble breathing;
  • Tension in chest;
  • Puffiness of the eyes, hands, face, tongue, mouth or lips;
  • Huskiness;
  • Chest ache;
  • Dark urination;
  • Decrease in urination;
  • Trouble swallowing;
  • Infections (e.g., chills, fever, unrelenting sore throat);
  • Unbalanced or sluggish heartbeats;
  • Stomach ache (without or with unsettled stomach or vomiting);
  • Indications of stumpy blood pressure (for e.g., severe dizziness, fainting, wooziness);
  • Yellowing in the eyes or skin.
  • Body aches,
  • Symptoms of flu;
  • Tired sensation,
  • Weakness in muscle,
  • Throbbing or irregular heartbeats;
  • Inflammation, quick gain in weight


Drugs That Have an Effect on Lisinopril:

Prior to taking lisinopril, inform your health care provider in case you’re using any of the subsequent medications:

lithium (Eskalith, Lithobid);

any gold injection made use of to cure arthritis;

salt replacements that hold potassium;

any potassium appendage for instance Klor-Con, K-Dur;

diabetes or insulin medication you consume by mouth;

any diuretic (water tablet).

aspirin or additional NSAIDs for instance diclofenac (Voltaren), ibuprofen (Advil, Motrin), indomethacin (Indocin), etodolac (Lodine), naproxen (Naprosyn, Aleve),  ketoprofen (Orudis), and others;

If you’re taking any of the above mentioned drugs, you might not be capable to take lisinopril or you might need prescribed amount adjustments or particular tests for the duration of treatment.


Indications for this drug:

  • Hypertension- Lisinopril tablets are indicated for cure of hypertension. Lisinopril might be made use of unaccompanied as an initial remedy or concomitantly along with other class of antihypertensive agent.
  • Heart malfunction- Lisinopril tablets are made use of as adjunctive healing in the administration of heart malfunction in patients who’re not responding satisfactorily to digitalis and diuretics.
  • Acute Myocardial Infarction- the drug is indicated for cure of hemodynamically secure patients contained by 24 hours of acute myocardial infarction, to advance endurance. Patients must receive, as suitable, the customary recommended treatment for instance beta-blockers, thrombolytics, and aspirin.


Mechanism of Action:

It causes inhibition of ACE to reduce levels of ATII and aldo-sterone. It also causes peripheral vasodilation and reduces total peripheral resistance (TPR). Blood pressure reduction is increased by decreased salt and water retention. Reduces after load in CHF and also decreases post capillary wedge pressure.


Onset of Effect:

Within 1-2 hours


Duration of Action:

Up to 24 hours


Adverse Effects:

  • Hypotension
  • Renal failure
  • Dizziness
  • Headaches
  • Diarrhea
  • Hyperkalaemia
  • Angioedema

Special Precautions:

Use cautiously in renal dysfunction, major surgical procedures or anaesthesia, in severe cardiac failure, sudden hypotension may lead to oliguria and acute renal failure. Reduce dose in elderly patients.


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